Duchenne muscular dystrophy cell culture models created by CRISPR/Cas9 gene editing and their application in drug screening 

Duchenne muscular dystrophy cell culture models created by CRISPR/Cas9 gene editing and their application in drug screening 

Abstract Gene editing methods are an attractive therapeutic option for Duchenne muscular dystrophy, and they have an immediate application in the generation of research models. To generate myoblast cultures that could be useful in in vitro drug screening, we have optimised a CRISPR/Cas9 gene edition...

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Bibliographic Details
Main Authors: Patricia Soblechero-Martín, Edurne Albiasu-Arteta, Aina Anton-Martinez, Laura de la Puente-Ovejero, Iker Garcia-Jimenez, Gabriela González-Iglesias, Irene Larrañaga-Aiestaran, Andrea López-Martínez, Javier Poyatos-García, Estíbaliz Ruiz-Del-Yerro, Federico Gonzalez, Virginia Arechavala-Gomeza
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-97730-5

Internet

https://doi.org/10.1038/s41598-021-97730-5

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