Developmental and loco-like effects of a swainsonine-induced inhibition of α-mannosidase in the honey bee, Apis mellifera

Background Deficiencies in lysosomal a-mannosidase (LAM) activity in animals, caused either by mutations or by consuming toxic alkaloids, lead to severe phenotypic and behavioural consequences. Yet, epialleles adversely affecting LAM expression exist in the honey bee population suggesting that they...

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Bibliographic Details
Main Authors: Laura Wedd, Regan Ashby, Sylvain Foret, Ryszard Maleszka
Format: Article
Language:English
Published: PeerJ Inc. 2017-03-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/3109.pdf