Knockdown of Decoy Receptor 3 Impairs Growth and Invasiveness of Hepatocellular Carcinoma Cell Line of HepG2

Knockdown of Decoy Receptor 3 Impairs Growth and Invasiveness of Hepatocellular Carcinoma Cell Line of HepG2

Background: Decoy receptor 3 (DcR3) binds to Fas ligand (FasL) and inhibits FasL-induced apoptosis. The receptor is overexpressed in hepatocellular carcinoma (HCC), and it is associated with the growth and metastatic spread of tumors. DcR3 holds promises as a new target for the treatment of HCC, but...

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Bibliographic Details
Main Authors: Xiao-Na Zhou, Guang-Ming Li, Ying-Chen Xu, Tuan-Jie Zhao, Ji-Xiang Wu
Format: Article
Language:English
Published: Wolters Kluwer 2016-01-01
Series:Chinese Medical Journal
Subjects:
Decoy Receptor 3; Hepatocellular Carcinoma; Matrix Metalloproteinase 9; Neoplasm Metastasis; Vascular Endothelial Growth Factor C; Vascular Endothelial Growth Factor D
Online Access:http://www.cmj.org/article.asp?issn=0366-6999;year=2016;volume=129;issue=21;spage=2623;epage=2629;aulast=Zhou

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http://www.cmj.org/article.asp?issn=0366-6999;year=2016;volume=129;issue=21;spage=2623;epage=2629;aulast=Zhou

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