A computational model for predicting nanoparticle accumulation in tumor vasculature.

Vascular targeting of malignant tissues with systemically injected nanoparticles (NPs) holds promise in molecular imaging and anti-angiogenic therapies. Here, a computational model is presented to predict the development of tumor neovasculature over time and the specific, vascular accumulation of bl...

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Bibliographic Details
Main Authors: Hermann B Frieboes, Min Wu, John Lowengrub, Paolo Decuzzi, Vittorio Cristini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3585411?pdf=render