Lysophosphatidic acid alters the expression profiles of angiogenic factors, cytokines, and chemokines in mouse liver sinusoidal endothelial cells.

Lysophosphatidic acid (LPA) is a multi-function glycerophospholipid. LPA affects the proliferation of hepatocytes and stellate cells in vitro, and in a partial hepatectomy induced liver regeneration model, the circulating LPA levels and LPA receptor (LPAR) expression levels in liver tissue are signi...

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Main Authors: Chia-Hung Chou, Shou-Lun Lai, Cheng-Maw Ho, Wen-Hsi Lin, Chiung-Nien Chen, Po-Huang Lee, Fu-Chuo Peng, Sung-Hsin Kuo, Szu-Yuan Wu, Hong-Shiee Lai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4379007?pdf=render