A comparative study of topology-based pathway enrichment analysis methods

Abstract Background Pathway enrichment extensively used in the analysis of Omics data for gaining biological insights into the functional roles of pre-defined subsets of genes, proteins and metabolites. A large number of methods have been proposed in the literature for this task. The vast majority o...

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Bibliographic Details
Main Authors: Jing Ma, Ali Shojaie, George Michailidis
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-019-3146-1