Target Misfolded Protein Clearance Pathway for Cancer Therapy
The role of RNA-dependent protein kinase R (PKR) and its association with misfolded protein expression in cancer cells are unclear. Herein we report that PKR regulates misfolded protein clearance by preventing it release through exosomes and promoting lysosomal degradation of misfolded prion protein...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-01-01
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| Series: | Proceedings |
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| Online Access: | https://www.mdpi.com/2504-3900/40/1/45 |