Transforming growth factor beta 1 levels predict echocardiographic changes at three years after adjuvant radiotherapy for breast cancer

Transforming growth factor beta 1 levels predict echocardiographic changes at three years after adjuvant radiotherapy for breast cancer

Abstract Background Transforming growth factor beta 1 (TGF-β1) and platelet-derived growth factor (PDGF) are cytokines involved in fibrotic processes causing radiotherapy (RT)-induced cardiovascular changes. We aimed to investigate the associations between TGF-β1 and PDGF and the echocardiographic c...

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Bibliographic Details
Main Authors: Hanna Aula, Tanja Skyttä, Suvi Tuohinen, Tiina Luukkaala, Mari Hämäläinen, Vesa Virtanen, Pekka Raatikainen, Eeva Moilanen, Pirkko-Liisa Kellokumpu-Lehtinen
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Radiation Oncology
Subjects:
Transforming growth factor beta 1
Platelet-derived growth factor
Cardiotoxicity
Breast cancer
Radiotherapy
Echocardiography
Online Access:http://link.springer.com/article/10.1186/s13014-019-1366-1

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http://link.springer.com/article/10.1186/s13014-019-1366-1

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