The p250GAP gene is associated with risk for schizophrenia and schizotypal personality traits.

The p250GAP gene is associated with risk for schizophrenia and schizotypal personality traits.

BACKGROUND: Hypofunction of the glutamate N-Methyl-d-aspartate (NMDA) receptor has been implicated in the pathophysiology of schizophrenia. p250GAP is a brain-enriched NMDA receptor-interacting RhoGAP. p250GAP is involved in spine morphology, and spine morphology has been shown to be altered in the...

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Bibliographic Details
Main Authors: Kazutaka Ohi, Ryota Hashimoto, Takanobu Nakazawa, Takeya Okada, Yuka Yasuda, Hidenaga Yamamori, Motoyuki Fukumoto, Satomi Umeda-Yano, Masao Iwase, Hiroaki Kazui, Tadashi Yamamoto, Masanobu Kano, Masatoshi Takeda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3329470?pdf=render

Internet

http://europepmc.org/articles/PMC3329470?pdf=render

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