Surfactant delivery in rat lungs: Comparing 3D geometrical simulation model with experimental instillation.

Surfactant Replacement Therapy (SRT), which involves instillation of a liquid-surfactant mixture directly into the lung airway tree, is a major therapeutic treatment in neonatal patients with respiratory distress syndrome (RDS). This procedure has proved to be remarkably effective in premature newbo...

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Bibliographic Details
Main Authors: Alireza Kazemi, Bruno Louis, Daniel Isabey, Gary F Nieman, Louis A Gatto, Joshua Satalin, Sarah Baker, James B Grotberg, Marcel Filoche
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-10-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007408