Inactivated Lactobacillus plantarum Carrying a Surface-Displayed Ag85B-ESAT-6 Fusion Antigen as a Booster Vaccine Against Mycobacterium tuberculosis Infection

Inactivated Lactobacillus plantarum Carrying a Surface-Displayed Ag85B-ESAT-6 Fusion Antigen as a Booster Vaccine Against Mycobacterium tuberculosis Infection

Vaccination is considered the most effective strategy for controlling tuberculosis (TB). The existing vaccine, the Bacille Calmette-Guérin (BCG), although partially protective, has a number of limitations. Therefore, there is a need for developing new TB vaccines and several strategies are currently...

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Bibliographic Details
Main Authors: Katarzyna Kuczkowska, Alastair Copland, Lise Øverland, Geir Mathiesen, Andy C. Tran, Mathew J. Paul, Vincent G. H. Eijsink, Rajko Reljic
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
tuberculosis
vaccine
lactic acid bacteria
Lactobacillus plantarum
adjuvant
delivery vector
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01588/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01588/full

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