ATRA attenuate proteinuria via downregulation of TRPC6 in glomerulosclerosis rats induced by adriamycin

ATRA attenuate proteinuria via downregulation of TRPC6 in glomerulosclerosis rats induced by adriamycin

Objective: In this research, we explored the molecular mechanism of proteinuria in glomerulosclerosis rats and the protective effects of ATRA. Methods: This research set up three groups: SHO group, GS group, and ATRA group (15 mg/(kg d), Sigma, St. Louis, MO). The serum creatinine (Scr), urea nitrog...

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Bibliographic Details
Main Authors: Lei Zhang, Xiu-Ping Chen, He Qin, Ling Jiang, Yuan-Han Qin
Format: Article
Language:English
Published: Taylor & Francis Group 2018-10-01
Series:Renal Failure
Subjects:
ATRA
glomerulosclerosis
proteinuria
TRPC6
Online Access:http://dx.doi.org/10.1080/0886022X.2018.1456459

Internet

http://dx.doi.org/10.1080/0886022X.2018.1456459

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