Curcumin attenuates beta-amyloid-induced neuroinflammation via activation of peroxisome proliferator-activated receptor-gamma function in a rat model of Alzheimer’s disease

Neuroinflammation is known to have a pivotal role in the pathogenesis of Alzheimer’s disease (AD), and curcumin has been reported to have therapeutical effects on AD because of its anti-inflammatory effects. Curcumin is not only a potent PPARγ agonist, but also has neuroprotective effects on cerebra...

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Bibliographic Details
Main Authors: Zun-Jing Liu, Zhong-Hao Li, Lei Liu, Wen-Xiong Tang, Yu Wang, Cheng Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00261/full