Hematological shift in goat kids naturally devoid of prion protein

Hematological shift in goat kids naturally devoid of prion protein

The physiological role of the cellular prion protein (PrPC) is incompletely understood. The expression of PrPC in hematopoietic stem cells and immune cells suggests a role in the development of these cells, and in PrPC knockout animals altered immune cell proliferation and phagocytic function have b...

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Bibliographic Details
Main Authors: Malin Rokseth Reiten, Maren Kolltveit Bakkebø, Hege eBrun-Hansen, Anna eLewandowska-Sabat, Ingrid eOlsaker, Michael Andreas Tranulis, Arild eEspenes, Preben eBoysen
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Hematopoiesis
Phagocytosis
cellular prion protein
T-Cell proliferation
PrpC
Hematological shift
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcell.2015.00044/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcell.2015.00044/full

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