Identification of Morphine and Heroin-Treatment in Mice Using Metabonomics

Although heroin and morphine are structural analogues and morphine is a metabolite of heroin, it is not known how the effect of each substance on metabolites in vivo differs. Heroin and morphine were administered to C57BL/6J mice in increasing doses from 2 to 25 and 3 to 9 mg kg<sup>−1</sup...

Full description

Bibliographic Details
Main Authors: Wuhuan Lu, Ran Zhang, Wei Sheng, Luohua Feng, Peng Xu, Youmei Wang, Yuan Xie, Hui Xu, Guangji Wang, Jiye Aa
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/11/9/607