Stereochemical Determination of Fistularins Isolated from the Marine Sponge <i>Ecionemia acervus</i> and Their Regulatory Effect on Intestinal Inflammation

Stereochemical Determination of Fistularins Isolated from the Marine Sponge <i>Ecionemia acervus</i> and Their Regulatory Effect on Intestinal Inflammation

By activity-guided fractionation based on inhibition of nitric oxide (NO) and prostaglandin E2 (PGE<sub>2</sub>), six fistularin compounds (<b>1</b>–<b>6</b>) were isolated from the marine sponge <i>Ecionemia acervus</i> (order Astrophorida). Based on...

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Bibliographic Details
Main Authors: Yeong Kwang Ji, Seon Min Lee, Na-Hyun Kim, Nguyen Van Tu, Yun Na Kim, Jeong Doo Heo, Eun Ju Jeong, Jung-Rae Rho
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Marine Drugs
Subjects:
fistularin
bromotyrosine alkaloid
<i>Ecionmeia acervus</i>
inflammatory bowel disease
co-culture
Mosher’s ester
Online Access:https://www.mdpi.com/1660-3397/19/3/170

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https://www.mdpi.com/1660-3397/19/3/170

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