Depletion of VPS35 attenuates metastasis of hepatocellular carcinoma by restraining the Wnt/PCP signaling pathway

Vesicle Protein Sorting 35 (VPS35) is a novel oncogene that promotes tumor growth through the PI3K/AKT signaling in hepatocellular carcinoma (HCC). However, the role of VPS35 in HCC metastasis and the underlying mechanisms remain largely unclear. In this study, we observed that overexpression of VPS...

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Bibliographic Details
Main Authors: Yi Liu, Haijun Deng, Li Liang, Guiji Zhang, Jie Xia, Keyue Ding, Ni Tang, Kai Wang
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Genes and Diseases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304220300921