A sensitive and specific method for measurement of multiple retinoids in human serum with UHPLC-MS/MS

Retinol (vitamin A) circulates at 1–4 μM concentration and is easily measured in serum. However, retinol is biologically inactive. Its metabolite, retinoic acid (RA), is believed to be responsible for biological effects of vitamin A, and hence the measurement of retinol concentrations is of limited...

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Bibliographic Details
Main Authors: Samuel L.M. Arnold, John K. Amory, Thomas J. Walsh, Nina Isoherranen
Format: Article
Language:English
Published: Elsevier 2012-03-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520413756