Rationale and methods of a randomized trial evaluating the effect of neprilysin inhibition on left ventricular remodelling

Rationale and methods of a randomized trial evaluating the effect of neprilysin inhibition on left ventricular remodelling

Abstract Aims In patients at high risk of heart failure following myocardial infarction (MI) as a result of residual left ventricular systolic dysfunction (LVSD), the angiotensin receptor neprilysin inhibitor sacubitril/valsartan may result in a greater attenuation of adverse left ventricular (LV) r...

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Bibliographic Details
Main Authors: Kieran F. Docherty, Ross T. Campbell, Katriona J.M. Brooksbank, Rosemary L. Godeseth, Paul Forsyth, Alex McConnachie, Giles Roditi, Bethany Stanley, Paul Welsh, Pardeep S. Jhund, Mark C. Petrie, John J.V. McMurray
Format: Article
Language:English
Published: Wiley 2021-02-01
Series:ESC Heart Failure
Subjects:
Clinical trial
Heart failure
Myocardial infarction
Natriuretic peptides
Neprilysin
Renin angiotensin aldosterone system
Online Access:https://doi.org/10.1002/ehf2.13137

Internet

https://doi.org/10.1002/ehf2.13137

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