Metabolic nuclear receptors coordinate energy metabolism to regulate Sox9+ hepatocyte fate

Summary: Recent research has indicated the adult liver Sox9+ cells located in the portal triads contribute to the physiological maintenance of liver mass and injury repair. However, the physiology and pathology regulation mechanisms of adult liver Sox9+ cells remain unknown. Here, PPARα and FXR boun...

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Bibliographic Details
Main Authors: Shenghui Liu, Dan Qin, Yi Yan, Jiayan Wu, Lihua Meng, Wendong Huang, Liqiang Wang, Xiangmei Chen, Lisheng Zhang
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221009718