The Structure and Biological Function of CREG

The Structure and Biological Function of CREG

The cellular repressor of E1A-stimulated genes (CREG) is a 220 amino acid glycoprotein structurally similar to oxidoreductases. However, CREG does not have enzymatic activities because it cannot bind to the cofactor flavin mononucleotide. Although CREG can be secreted, it is mainly an intracellular...

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Bibliographic Details
Main Authors: Gaby Ghobrial, Luiz Araujo, Felecia Jinwala, Shaohua Li, Leonard Y. Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
CREG
mannose-6-phosphate/insulin-like growth factor-2 receptor
exocyst
lysosome
proliferation
differentiation
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2018.00136/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2018.00136/full

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