CircRNA_0001449 disturbs phosphatidylinositol homeostasis and AKT activity by enhancing Osbpl5 translation in transient cerebral ischemia

CircRNA_0001449 disturbs phosphatidylinositol homeostasis and AKT activity by enhancing Osbpl5 translation in transient cerebral ischemia

Phosphatidylinositol-3,4,5-trisphosphate [PI(3,4,5)P3] is a phosphorylated derivative of phosphatidylinositol 4-phosphate [PI(4)P] and phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2], which recruit and activate AKT in the plasma membrane (PM) to promote cellular survival. ORP5 anchors at the endop...

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Bibliographic Details
Main Authors: Fei-Fei Shang, Li Luo, Jianghong Yan, Qiubo Yu, Yongzheng Guo, Yuchen Wen, Xiao-Li Min, Ling Jiang, Xiang He, Wei Liu
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Redox Biology
Subjects:
Cerebral ischemia
Lipids and lipoprotein metabolism
Non-coding RNA
AKT
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231719315976

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http://www.sciencedirect.com/science/article/pii/S2213231719315976

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