Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies

Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies

Summary: Human pluripotent stem cells (hPSCs) provide an invaluable tool for modeling diseases and hold promise for regenerative medicine. For understanding pluripotency and lineage differentiation mechanisms, a critical first step involves systematically cataloging essential genes (EGs) that are in...

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Bibliographic Details
Main Authors: Barbara Mair, Jelena Tomic, Sanna N. Masud, Peter Tonge, Alexander Weiss, Matej Usaj, Amy Hin Yan Tong, Jamie J. Kwan, Kevin R. Brown, Emily Titus, Michael Atkins, Katherine S.K. Chan, Lise Munsie, Andrea Habsid, Hong Han, Marion Kennedy, Brenda Cohen, Gordon Keller, Jason Moffat
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719302128

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http://www.sciencedirect.com/science/article/pii/S2211124719302128

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