Exploring Biased Agonism at FPR1 as a Means to Encode Danger Sensing
Ligand-based selectivity in signal transduction (biased signaling) is an emerging field of G protein-coupled receptor (GPCR) research and might allow the development of drugs with targeted activation profiles. Human formyl peptide receptor 1 (FPR1) is a GPCR that detects potentially hazardous states...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-04-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/9/4/1054 |