Insulin gene expression is regulated by DNA methylation.

BACKGROUND:Insulin is a critical component of metabolic control, and as such, insulin gene expression has been the focus of extensive study. DNA sequences that regulate transcription of the insulin gene and the majority of regulatory factors have already been identified. However, only recently have...

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Bibliographic Details
Main Authors: Akio Kuroda, Tibor A Rauch, Ivan Todorov, Hsun Teresa Ku, Ismail H Al-Abdullah, Fouad Kandeel, Yoko Mullen, Gerd P Pfeifer, Kevin Ferreri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2735004?pdf=render