JARID1B promotes colorectal cancer proliferation and Wnt/β-catenin signaling via decreasing CDX2 level

JARID1B promotes colorectal cancer proliferation and Wnt/β-catenin signaling via decreasing CDX2 level

Abstract Background Jumonji AT-rich interactive domain 1B(JARID1B) has been shown to be upregulated in many human cancers and plays a critical role in the development of cancers cells. Nevertheless, its functional role in colorectal cancer (CRC) progression is not fully understood. Methods Herein, J...

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Bibliographic Details
Main Authors: Da Huang, Fan Xiao, Haibin Hao, Fuzhou Hua, Zhenzhong Luo, Zhaoxia Huang, Qing Li, Sha Chen, Xiuzhi Cheng, Xinyue Zhang, Weilan Fang, Xiaoyun Hu, Fanrong Liu
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Cell Communication and Signaling
Subjects:
Colorectal cancer
Cell proliferation
JARID1B
CDX2
H3K4me3
Wnt/β-catenin
Online Access:http://link.springer.com/article/10.1186/s12964-020-00660-4

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http://link.springer.com/article/10.1186/s12964-020-00660-4

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