Copy number variant analysis and expression profiling of the olfactory receptor-rich 11q11 region in obesity predisposition

Copy number variant analysis and expression profiling of the olfactory receptor-rich 11q11 region in obesity predisposition

Genome-wide copy number surveys associated chromosome 11q11 with obesity. As this is an olfactory receptor-rich region, we hypothesize that genetic variation in olfactory receptor genes might be implicated in the pathogenesis of obesity. Multiplex Amplicon Quantification analysis was applied to scre...

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Bibliographic Details
Main Authors: Sara Diels, Sander Huybreghts, Kim Van Hoorenbeeck, Guy Massa, An Verrijken, Stijn L. Verhulst, Luc F. Van Gaal, Wim Van Hul
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Molecular Genetics and Metabolism Reports
Subjects:
Obesity
Olfactory receptor
Copy number variant
Chromosome 11q11
Expression profiling
Online Access:http://www.sciencedirect.com/science/article/pii/S2214426920301026

Internet

http://www.sciencedirect.com/science/article/pii/S2214426920301026

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