Pharmacological activation of CB2 receptors counteracts the deleterious effect of ethanol on cell proliferation in the main neurogenic zones of the adult rat brain

Pharmacological activation of CB2 receptors counteracts the deleterious effect of ethanol on cell proliferation in the main neurogenic zones of the adult rat brain

Chronic alcohol exposure reduces endocannabinoid activity and disrupts adult neurogenesis in rodents, which results in structural and functional alterations. Cannabinoid receptor agonists promote adult neural progenitor cell (NPC) proliferation. We evaluated the protective effects of the selective C...

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Bibliographic Details
Main Authors: Patricia eRivera, Eduardo eBlanco, Laura eBindila, Francisco eAlen, Antonio eVargas, Leticia eRubio, FRANCISCO JAVIER ePAVON, Antonia eSerrano, Beat eLutz, FERNANDO eRODRIGUEZ DE FONSECA, JUAN eSUAREZ
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Neurogenesis
alcohol
CB1 receptor
ACEA
CB2 receptor
JWH133
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00379/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00379/full

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