Kindlin-2 Modulates the Survival, Differentiation, and Migration of Induced Pluripotent Cell-Derived Mesenchymal Stromal Cells

Kindlin-2 is a multidomain intracellular protein that can be recruited to β-integrin domains to activate signaling, initiate transcriptional programs, and bind to E-cadherin. To explore its involvement in cell fate decisions in mesenchymal cells, we studied the effects of Kindlin-2 modification (ove...

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Bibliographic Details
Main Authors: Mohsen Moslem, Reto Eggenschwiler, Christian Wichmann, Raymund Buhmann, Tobias Cantz, Reinhard Henschler
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2017/7316354