Functional Role of SIL1 in Neurodevelopment and Learning

Background. Sil1 is the causative gene of Marinesco-Sjӧgren Syndrome (MSS). The mutated Sil1 generates shortened SIL1 protein which will form aggregation and be degraded rapidly. Mental retardation is a major symptom of MSS which suggests a role of SIL1 in the development of the central nervous syst...

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Bibliographic Details
Main Authors: Shilian Xu, Jia Zhu, Kai Mi, Yan Shen, Xiaomin Zhang
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2019/9653024