Decreased phenol sulfotransferase activities associated with hyperserotonemia in autism spectrum disorders

Abstract Hyperserotonemia is the most replicated biochemical abnormality associated with autism spectrum disorders (ASD). However, previous studies of serotonin synthesis, catabolism, and transport have not elucidated the mechanisms underlying this hyperserotonemia. Here we investigated serotonin su...

Full description

Bibliographic Details
Main Authors: Cécile Pagan, Marion Benabou, Claire Leblond, Freddy Cliquet, Alexandre Mathieu, Nathalie Lemière, Hany Goubran-Botros, Richard Delorme, Marion Leboyer, Jacques Callebert, Thomas Bourgeron, Jean-Marie Launay
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-020-01125-5