The outcome of renal ischemia-reperfusion injury is unchanged in AMPK-β1 deficient mice.

The outcome of renal ischemia-reperfusion injury is unchanged in AMPK-β1 deficient mice.

AIM: Activation of the master energy-regulator AMP-activated protein kinase (AMPK) in the heart reduces the severity of ischemia-reperfusion injury (IRI) but the role of AMPK in renal IRI is not known. The aim of this study was to determine whether activation of AMPK by acute renal ischemia influenc...

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Bibliographic Details
Main Authors: Peter F Mount, Kurt Gleich, Shanna Tam, Scott A Fraser, Suet-Wan Choy, Karen M Dwyer, Bo Lu, Bryce Van Denderen, Günter Fingerle-Rowson, Richard Bucala, Bruce E Kemp, David A Power
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3253796?pdf=render

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http://europepmc.org/articles/PMC3253796?pdf=render

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