Therapeutic effect and autophagy regulation of myriocin in nonalcoholic steatohepatitis

Therapeutic effect and autophagy regulation of myriocin in nonalcoholic steatohepatitis

Abstract Background Ceramide plays pathogenic roles in nonalcoholic fatty liver disease (NAFLD) via multiple mechanisms, and as such inhibition of ceramide de novo synthesis in the liver may be of therapeutically beneficial in patients with NAFLD. In this study, we aimed to explore whether inhibitio...

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Main Authors: Rui-Xu Yang, Qin Pan, Xiao-Lin Liu, Da Zhou, Feng-Zhi Xin, Ze-Hua Zhao, Rui-Nan Zhang, Jing Zeng, Liang Qiao, Chun-Xiu Hu, Guo-Wang Xu, Jian-Gao Fan
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Lipids in Health and Disease
Subjects:
Ceramides
Autophagy
High fat diet
Non-alcoholic fatty liver disease
Online Access:http://link.springer.com/article/10.1186/s12944-019-1118-0

Internet

http://link.springer.com/article/10.1186/s12944-019-1118-0

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