The photodecarboxylative addition of carboxylates to phthalimides as a key-step in the synthesis of biologically active 3-arylmethylene-2,3-dihydro-1H-isoindolin-1-ones

The photodecarboxylative addition of carboxylates to phthalimides as a key-step in the synthesis of biologically active 3-arylmethylene-2,3-dihydro-1H-isoindolin-1-ones

The synthesis of various 3-arylmethylene-2,3-dihydro-1H-isoindolin-1-ones was realized following a simple three-step process. The protocol utilized the photodecarboxylative addition of readily available carboxylates to N-(bromoalkyl)phthalimides as a versatile and efficient key step. The initially o...

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Bibliographic Details
Main Authors: Ommid Anamimoghadam, Saira Mumtaz, Anke Nietsch, Gaetano Saya, Cherie A. Motti, Jun Wang, Peter C. Junk, Ashfaq Mahmood Qureshi, Michael Oelgemöller
Format: Article
Language:English
Published: Beilstein-Institut 2017-12-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
anesthetics
arylmethylenedihydroisoindolinones
photochemistry
photodecarboxylation
phthalimide
Online Access:https://doi.org/10.3762/bjoc.13.275

Internet

https://doi.org/10.3762/bjoc.13.275

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