TCF4 Is a Molecular Target of Resveratrol in the Prevention of Colorectal Cancer

The Wnt/β-catenin pathway plays an essential role in the tumorigenesis of colorectal cancer. T-cell factor-4 (TCF4) is a member of the TCF/LEF (lymphoid enhancer factor) family of transcription factors, and dysregulation of β-catenin is decisive for the initiation and progression of colorectal cance...

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Bibliographic Details
Main Authors: Jin Boo Jeong, Jihye Lee, Seong-Ho Lee
Format: Article
Language:English
Published: MDPI AG 2015-05-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/16/5/10411