CD3+CD4negCD8neg (double negative) T lymphocytes and NKT cells as the main cytotoxic-related-CD107a+ cells in lesions of cutaneous leishmaniasis caused by Leishmania (Viannia) braziliensis

CD3+CD4negCD8neg (double negative) T lymphocytes and NKT cells as the main cytotoxic-related-CD107a+ cells in lesions of cutaneous leishmaniasis caused by Leishmania (Viannia) braziliensis

Abstract Background Cutaneous leishmaniasis (CL) is caused by Leishmania (Viannia) braziliensis, which infects dermal macrophages and dendritic cells, causing an intense immune-mediated-tissue inflammation and a skin ulcer with elevated borders that can heal spontaneously or after antimonial therapy...

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Bibliographic Details
Main Authors: Raquel Ferraz, Clarissa F. Cunha, Maria Inês F. Pimentel, Marcelo R. Lyra, Tatiana Pereira-Da-Silva, Armando O. Schubach, Alda Maria Da-Cruz, Alvaro Luiz Bertho
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Parasites & Vectors
Subjects:
Flow cytometry
Cytotoxicity
CD107a
Double-negative T lymphocytes
NKT cells
Lesion
Online Access:http://link.springer.com/article/10.1186/s13071-017-2152-2

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http://link.springer.com/article/10.1186/s13071-017-2152-2

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