18F-labeled Pyrazolo[1,5-a]pyrimidine Derivatives: Synthesis from 2,4-Dinitrobenzamide and Tosylate Precursors and Comparative Biological Evaluation for Tumor Imaging with Positron Emission Tomography

18F-labeled Pyrazolo[1,5-a]pyrimidine Derivatives: Synthesis from 2,4-Dinitrobenzamide and Tosylate Precursors and Comparative Biological Evaluation for Tumor Imaging with Positron Emission Tomography

We previously reported 18F-labeled pyrazolo[1,5-a]pyrimidine derivatives: 7-(2-[18F]fluoroethylamino)-5-methylpyrazolo[1,5-a]pyrimidine-3-carbonitrile ([18F]1) and N-(2-(3-cyano-5-methylpyrazolo[1,5-a]pyrimidin-7-ylamino)ethyl)-2-[18F]fluoro-4-nitro- benzamide ([18F]2). Preliminary biodistribution e...

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Bibliographic Details
Main Authors: Chuanmin Qi, Yingruo Li, Mingxia Zhao, Shilei Li, Yurong Chen, Shuting Zhang, Man Feng, Xiao Wang, Rui Ding, Yong He, Guixia Li, Hang Liu, Jingli Xu, Yonghong Dang
Format: Article
Language:English
Published: MDPI AG 2012-03-01
Series:Molecules
Subjects:
18F-labeled
pyrazolo[1,5-a]pyrimidine derivatives
2,4-dinitrobenzamide and tosylate precursors
PET imaging agents
tumor detection
Online Access:http://www.mdpi.com/1420-3049/17/4/3774/

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http://www.mdpi.com/1420-3049/17/4/3774/

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