In global health research, is it legitimate to stop clinical trials early on account of their opportunity costs?

BACKGROUND TO THE DEBATE: After the failure of three large clinical trials of vaginal microbicides, a Nature editorial stated that the microbicide field "requires a mechanism to help it make rational choices about the best candidates to move through trials" [1]. In this month's debate...

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Bibliographic Details
Main Authors: James V Lavery, Peter A Singer, Renee Ridzon, Jerome A Singh, Arthur S Slutsky, Joseph J Anisko, David Buchanan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC2686164?pdf=render