Multivalent HA DNA vaccination protects against highly pathogenic H5N1 avian influenza infection in chickens and mice.

Multivalent HA DNA vaccination protects against highly pathogenic H5N1 avian influenza infection in chickens and mice.

Sustained outbreaks of highly pathogenic avian influenza (HPAI) H5N1 in avian species increase the risk of reassortment and adaptation to humans. The ability to contain its spread in chickens would reduce this threat and help maintain the capacity for egg-based vaccine production. While vaccines off...

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Bibliographic Details
Main Authors: Srinivas Rao, Wing-Pui Kong, Chih-Jen Wei, Zhi-Yong Yang, Martha Nason, Darrel Styles, Louis J DeTolla, Aruna Panda, Erin M Sorrell, Haichen Song, Hongquan Wan, Gloria C Ramirez-Nieto, Daniel Perez, Gary J Nabel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2657001?pdf=render

Internet

http://europepmc.org/articles/PMC2657001?pdf=render

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