HIV-1 fusion inhibitor peptides enfuvirtide and T-1249 interact with erythrocyte and lymphocyte membranes.

Enfuvirtide and T-1249 are two HIV-1 fusion inhibitor peptides that bind to gp41 and prevent its fusogenic conformation, inhibiting viral entry into host cells. Previous studies established the relative preferences of these peptides for membrane model systems of defined lipid compositions. We aimed...

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Bibliographic Details
Main Authors: Pedro M Matos, Miguel A R B Castanho, Nuno C Santos
Format: Article
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
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