RNAseq Profiling of Leukocyte Populations in Zebrafish Larvae Reveals a cxcl11 Chemokine Gene as a Marker of Macrophage Polarization During Mycobacterial Infection

RNAseq Profiling of Leukocyte Populations in Zebrafish Larvae Reveals a cxcl11 Chemokine Gene as a Marker of Macrophage Polarization During Mycobacterial Infection

Macrophages are phagocytic cells from the innate immune system, which forms the first line of host defense against invading pathogens. These highly dynamic immune cells can adopt specific functional phenotypes, with the pro-inflammatory M1 and anti-inflammatory M2 polarization states as the two extr...

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Bibliographic Details
Main Authors: Julien Rougeot, Vincenzo Torraca, Ania Zakrzewska, Zakia Kanwal, Hans J. Jansen, Frida Sommer, Herman P. Spaink, Annemarie H. Meijer
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
innate immunity
zebrafish
RNAseq
macrophage
mycobacteria
neutrophil
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00832/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00832/full

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