A mutation in C. neoformans mitochondrial NADH dehydrogenase results in increased virulence in mice

Cryptococcus neoformans: (H99W) was serially passaged in the invertebrate wax moth Galleria mellonella fifteen times to study how fungal virulence evolves under selection and whether those adaptations affect virulence. The G. mellonella passaged strain (P15) and the pre-passage H99W strains were use...

Full description

Bibliographic Details
Main Authors: Mitch Merryman, Jacob Crigler, Rebecca Seipelt-Thiemann, Erin McClelland
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Virulence
Subjects:
Online Access:http://dx.doi.org/10.1080/21505594.2020.1831332