Applications of Probe Capture Enrichment Next Generation Sequencing for Whole Mitochondrial Genome and 426 Nuclear SNPs for Forensically Challenging Samples

Applications of Probe Capture Enrichment Next Generation Sequencing for Whole Mitochondrial Genome and 426 Nuclear SNPs for Forensically Challenging Samples

The application of next generation sequencing (NGS) for the analysis of mitochondrial (mt) DNA, short tandem repeats (STRs), and single nucleotide polymorphism (SNPs) has demonstrated great promise for challenging forensic specimens, such as degraded, limited, and mixed samples. Target enrichment us...

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Bibliographic Details
Main Authors: Shelly Y. Shih, Nikhil Bose, Anna Beatriz R. Gonçalves, Henry A. Erlich, Cassandra D. Calloway
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Genes
Subjects:
Next Generation Sequencing (NGS)
Massively Parallel Sequencing (MPS)
Probe Capture Target Enrichment
mitochondrial DNA (mtDNA)
Single Nucleotide Polymorphism (SNP)
Forensic Genetics
degraded DNA
Online Access:http://www.mdpi.com/2073-4425/9/1/49

Internet

http://www.mdpi.com/2073-4425/9/1/49

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