Hypothalamic hormone-sensitive lipase regulates appetite and energy homeostasis

Objective: The goal of this study was to investigate the importance of central hormone-sensitive lipase (HSL) expression in the regulation of food intake and body weight in mice to clarify whether intracellular lipolysis in the mammalian hypothalamus plays a role in regulating appetite. Methods: Usi...

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Bibliographic Details
Main Authors: Cecilie Hundahl, Petra Kotzbeck, Hayley B. Burm, Søren H. Christiansen, Lola Torz, Aske W. Helge, Martin P. Madsen, Cecilia Ratner, Annette K. Serup, Jonatan J. Thompson, Thomas O. Eichmann, Tune H. Pers, David P.D. Woldbye, Daniele Piomelli, Bente Kiens, Rudolf Zechner, Louise J. Skov, Birgitte Holst
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Molecular Metabolism
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877821000144