Sequence determinants of innate immune activation by short interfering RNAs

Sequence determinants of innate immune activation by short interfering RNAs

<p>Abstract</p> <p>Background</p> <p>Short interfering RNAs (siRNAs) have been shown to induce immune stimulation through a number of different receptors in a range of cell types. In primary cells, both TLR7 and TLR8 have been shown to recognise siRNAs however, despite...

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Bibliographic Details
Main Authors: Poidinger Michael, Arndt Greg M, Tanudji Marcel, Doan Tram, King Andrew, Nopper Nicole, Goodchild Amber, Rivory Laurent P, Passioura Toby
Format: Article
Language:English
Published: BMC 2009-07-01
Series:BMC Immunology
Online Access:http://www.biomedcentral.com/1471-2172/10/40

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http://www.biomedcentral.com/1471-2172/10/40

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