Adaptation and preadaptation of Salmonella enterica to Bile.

Bile possesses antibacterial activity because bile salts disrupt membranes, denature proteins, and damage DNA. This study describes mechanisms employed by the bacterium Salmonella enterica to survive bile. Sublethal concentrations of the bile salt sodium deoxycholate (DOC) adapt Salmonella to surviv...

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Bibliographic Details
Main Authors: Sara B Hernández, Ignacio Cota, Adrien Ducret, Laurent Aussel, Josep Casadesús
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3261920?pdf=render