Identification of TMEM206 proteins as pore of PAORAC/ASOR acid-sensitive chloride channels
Acid-sensing ion channels have important functions in physiology and pathology, but the molecular composition of acid-activated chloride channels had remained unclear. We now used a genome-wide siRNA screen to molecularly identify the widely expressed acid-sensitive outwardly-rectifying anion channe...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-07-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/49187 |