Apoptosis of mesenchymal stem cells is regulated by Rspo1 via the Wnt/β-catenin signaling pathway

Objective: The aim of this study was to investigate the effect and possible mechanism of action of roof plate-specific spondin1 (Rspo1) in the apoptosis of rat bone marrow mesenchymal stem cells (BMSCs). Methods: Osteogenic and adipogenic differentiation of BMSCs was identified by Alizarin Red and O...

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Bibliographic Details
Main Authors: Xiao-Xia Cheng, Qiao-Yan Yang, Yong-Li Qi, Zhi-Zhen Liu, Dan Liu, Sheng He, Li-Hong Yang, Jun Xie
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2019-03-01
Series:Chronic Diseases and Translational Medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2095882X18301063