Non-antioxidant properties of α-tocopherol reduce the anticancer activity of several protein kinase inhibitors in vitro.

The antioxidant properties of α-tocopherol have been proposed to play a beneficial chemopreventive role against cancer. However, emerging data also indicate that it may exert contrasting effects on the efficacy of chemotherapeutic treatments when given as dietary supplement, being in that case harmf...

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Bibliographic Details
Main Authors: Stéphane Pédeboscq, Christophe Rey, Muriel Petit, Catherine Harpey, Francesca De Giorgi, François Ichas, Lydia Lartigue
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3348137?pdf=render