The GRA17 Parasitophorous Vacuole Membrane Permeability Pore Contributes to Bradyzoite Viability

The Toxoplasma gondii parasitophorous vacuole membrane (PVM) offers protection from the host immune system but is also a barrier for uptake of nutrients from the host. Previously, we showed that GRA17 mediates the tachyzoite PVM permeability to small molecules. During the conversion from tachyzoites...

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Bibliographic Details
Main Authors: Tatiana Paredes-Santos, Yifan Wang, Benjamin Waldman, Sebastian Lourido, Jeroen P. Saeij
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Cellular and Infection Microbiology
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Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00321/full